Update

The software used to work great, but now randomly the Tweet button no longer works. Only keyboard commands work for tweeting, closing the New Tweet windows and closing the image popup. Also at times I cant switch from my timeline to my lists. Tapbot support seems to be non existent.

update: Tapbot came through, one of my SIMBL bundles was causing the issue. Removing the bundle, and restarting the app has fixed the issues.

ianmurchison about Tweetbot for Twitter, v1.0.1